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The efficacy and role of baicalin and contraindications What is baicalin?

View: 57 Author: Site Editor Publish Time: 2022-09-16 Origin: site

Baicalin  is a kind of Chinese herbal medicine with very high medicinal value that we can often see in our life. Many people like to use baicalin to treat some diseases. But what kind of Chinese herbal medicine is baicalin? Let’s take a look at some of the effects of baicalin with the editor!

What is baicalin

The efficacy and role of baicalin

1. Anti-inflammatory, anti-allergic, anti-allergic, protect bone

Baicalin and baicalein have a significant inhibitory effect on joint inflammation, and baicalein has a significant inhibitory effect on rheumatoid arthritis and γ-globulin degeneration, and its mechanism of action is similar to D-penicillamine; Bone damage has a protective effect and can inhibit the degeneration and destruction of bone.

2. Antipyretic, detoxification and anti-pathogen

Scutellaria flavonoids have significant broad-spectrum antibacterial and antiviral effects and inhibition of amoeba. However, it has also been reported that Scutellaria baicalensis has no obvious antibacterial effect, or has a weak antibacterial effect.

3. Gallbladder, liver protection and lipid lowering

This product can promote the secretion of bile in rabbits and reduce the content of high bilirubin in the blood. Has a significant hepatoprotective effect. Scutellaria flavonoids can significantly reduce the elevated transaminases ALT and AST in animal serum.

Baicalein can significantly reduce serum total cholesterol and intrahepatic triglyceride in hyperlipidemia rats, and can inhibit the conversion of glucose to fat. Wogonin can significantly reduce intrahepatic and serum triglycerides, and can increase serum high-density lipoprotein. Wogonin, baicalein, and baicalin can also significantly reduce serum γ-GT, AlT, AST, TG, and Tch. Baicalin and baicalein can also inhibit the lipolysis of adipose tissue.

4. Influence on retinopathy

By establishing an animal model of inflammatory retinal edema, optical coherence tomography was used to continuously observe changes in the thickness of inflammatory retinal edema, and compared with the results of retinal morphological observation and retinal thickness measurement, baicalin inhibition was quantified from imaging and histology The effect of retinal inflammatory edema, and the effect of different concentrations of drugs were evaluated. Baicalin significantly inhibits retinal extracellular inflammatory edema and is not inferior to topical corticosteroids.

Contraindications of Baicalin

When taking baicalin, pay attention to the dosage and do not use too much.

What is baicalin

Baicalin is a flavonoid compound extracted and isolated from the dry root of Scutellaria baicalensis, a dicotyledonous Lamiaceae plant. It is a pale yellow powder at room temperature with a bitter taste. Insoluble in methanol, ethanol, acetone, slightly soluble in chloroform and nitrobenzene, almost insoluble in water, soluble in hot acetic acid. It is green in case of ferric chloride, and orange precipitate is formed in case of lead acetate. Soluble in alkali and ammonia water, it turns yellow at first, and soon becomes black-brown. It has significant biological activities, with antibacterial, diuretic, anti-inflammatory, cholesterol-lowering, anti-thrombotic, relieving asthma, purging fire and detoxification, hemostasis, tocolytic, anti-allergic and antispasmodic effects, and is also a mammalian liver salivary enzyme. Specific inhibitors have the effect of regulating certain diseases, and also have strong physiological efficacy of anti-cancer response.

pharmacological use

Baicalin is a flavonoid compound extracted and isolated from the root of Scutellaria baicalensis. It has significant biological activity, antibacterial, diuretic, anti-inflammatory, anti-allergic and antispasmodic effects, and has strong anti-cancer response and other physiological effects. . It has occupied an important position in clinical medicine. Baicalin can also absorb ultraviolet rays, scavenge oxygen free radicals, and inhibit the formation of melanin, so it can be used in both medicine and cosmetics, and is a good functional cosmetic raw material.

In general, the medicinal value of baicalin is still very strong, and it occupies a very important position in the field of traditional Chinese medicine. However, in the process of consuming astragaloside, you should also pay attention to its consumption taboos, and it is not advisable to consume too much.