Different pig diseases use different disinfectants
Disinfectants are classified into three categories according to their level of action: high-efficiency, medium-efficiency, and low-efficiency.
High-efficiency disinfectants are effective against viruses, bacteria, spores, fungi, etc., such as glutaraldehyde, sodium hydroxide, peracetic acid, etc., but they have large side effects and are not suitable for some disinfection; medium-effect disinfectants are effective for all bacteria , but ineffective against spores, such as ethanol, iodine preparations, etc.; low-efficiency disinfectants are bacteriostatic agents, and are also ineffective against spores, fungi, and hydrophilic viruses (non-enveloped viruses), such as quaternary ammonium salts.
At present, multiple infections or secondary infections of pathogenic microorganisms in large-scale pig farms are very common, including mixed infection of viruses, mixed infections of bacteria, mixed infections of viruses and bacteria, and some primary infections. secondary infection.
According to the investigation, there are porcine reproductive and respiratory syndrome virus, porcine circovirus type 2, foot-and-mouth disease virus, swine fever virus, pseudorabies virus, mycoplasma pneumoniae, streptococcus suis, actinobacillus pleuropneumoniae, and pastoral bacteria in large-scale pig farms. The threat of pathogenic microorganisms such as bacillus, porcine eperythrozoon, and Escherichia coli.
When choosing a disinfectant, it is necessary to exchange different types of drugs according to the disinfection object, purpose, and type of epidemic. For example, some viruses (no cytoplasmic virus in the structure) are not sensitive to common disinfectants, especially circoviruses, and general disinfectants do not work on them, and high-efficiency disinfectants should be selected.
Disinfectants that are highly irritating and corrosive to pigs should not be used, such as sodium hydroxide, to avoid damage to the skin of humans and animals; medium-effect disinfectants can be selected for disinfection of the injection site.
Due to the differences in biological characteristics such as the morphological structure and metabolic mode of pathogenic microorganisms themselves, their responses to disinfection performance are also different. For example, G+ bacteria are more sensitive to disinfectants than G- bacteria, because the cell wall of G- bacteria is formed by a rich lipid envelope, which has the effect of preventing the entry of disinfectants.
Therefore, for G-bacteria (such as Pasteurella multocida, Salmonella, Actinobacillus pleuropneumoniae, etc.), it is necessary to select a disinfectant with a stronger effect. For bacteria with spores (such as Bacillus anthracis), because the spores have thick spore walls and multi-layer spore membranes, the structure is solid, and the disinfectants are not easy to penetrate, so high-efficiency disinfectants should generally be selected.
Attachment: The selection of disinfectants is based on the sensitivity of the pathogen to a specific disinfectant.
Swine fever virus
Sensitive to alkaline disinfectants, such as caustic soda and quicklime, 2% caustic soda solution plus 5% salt water can be used for disinfection in winter.
Foot-and-mouth disease virus
is sensitive to both acidic and alkaline disinfectants, such as caustic soda.
PRRS virus
is sensitive to aldehyde disinfectants (formaldehyde, polyoxymethylene, etc.), chlorine-containing disinfectants (5% bleaching powder solution), and alkaline preparations (sodium hydroxide and quicklime, etc.).
Circovirus
has strong resistance to the external environment, but is sensitive to quaternary ammonium salt iodized disinfectant.
Pseudorabies virus
is sensitive to acidic, alkaline and iodized disinfectants.
Parvovirus
is sensitive to alkaline and 0.5% bleach solutions.
Japanese encephalitis virus
can be killed by commonly used disinfectants, such as biquaternary ammonium salts.
Rotavirus
is sensitive to chloroform and ether, but not to chemical reagents.
Influenza virus
is sensitive to phenolic disinfectants and ether, but it is best not to use phenolic disinfectants when there is respiratory disease; Actinobacillus pleuropneumoniae is sensitive to benzalkonium bromide.
The swine fever virus
is sensitive to alkaline disinfectants, such as caustic soda and quicklime. In winter, 2% caustic soda solution and 5% salt water can be used for disinfection.
Mycoplasma pneumoniae
is sensitive to diquat and iodine.
Pasteurella
is sensitive to caustic soda and benzalkonium bromide.
Streptococcus
is sensitive to benzalkonium bromide and a 3% bleach solution.
Salmonella
is sensitive to caustic soda and iodine-based disinfectants.
Escherichia coli
Sensitive to common disinfectants.
Haemophilus parasuis
is sensitive to commonly used disinfectants.