Application of Clostridium butyricum as feed additive in feed
Outbreaks of food-borne diseases have highlighted the need to reduce pathogenic bacteria in animal organs, animal intestinal pathogens are a direct source of food contamination, and widespread worldwide concern over the ability of antibiotic resistance genes to transfer from animals to humans has led to the European Union's decision to On January 1, the use of antibiotics as growth promoters was banned. Clostridium butyricum preparations become an ideal choice to replace antibiotics, which can not only reduce drug resistance and superinfection caused by the use of antibiotics, but also improve the natural defense mechanism and economic benefits of animals. The Ministry of Agriculture of my country approved the use of Clostridium butyricum preparations as microbial feed additives in July 2009.
1. As an animal probiotic preparation
Clostridium butyricum preparations have been used as feed additives for cattle, pigs and poultry in many countries. Many domestic studies have confirmed that the fermentation of Clostridium butyricum can acidify and soften feed, improve nutrients and palatability; seize the space niche and nutritional niche in animals with absolute advantages, produce a variety of probiotics, and improve feed utilization; keep animals Normalize the microbial flora in the intestinal tract, produce clostridium butyrate, inhibit harmful intestinal bacteria, improve animal disease resistance and immunity, reduce the death rate and reduce the content of NH3 and H2S in the feces.
2. Improve the production performance of animals
Clostridium butyricum preparations can reduce the use of antibiotic hormones in animal feed, improve the production performance of animals, increase the output of poultry meat, eggs and dairy products, and the fertilization rate, egg production, hatching rate and fry survival rate of fish. The length of poultry intestinal villi was significantly positively correlated with the number of intestinal epithelial cells. When the villi become longer, the number of intestinal epithelial cells increases, and the ability to digest and absorb nutrients increases. Adding 0.9% Clostridium butyricum to 1-day-old AA broiler chickens can significantly increase the length of intestinal villi, which can also significantly increase the average weight gain of broilers, and the incidence rate and mortality rate of the experimental group are significantly lower than those of the control group. When an appropriate amount of Clostridium butyricum was added to the feed of broilers, the pH of the cecal digest and the relative length of the cecum decreased significantly, and the alkaline phosphatase activity on the jejunal mucosa and the short-chain fatty acids in the cecum increased relatively, suggesting that edible oil and butyric acid Acidic Clostridium interacts to have a healthy effect on the intestinal tract of broilers.
Clostridium butyricum preparation can significantly improve the fertilization rate of various duck eggs. The mechanism is that Clostridium butyricum can produce a variety of vitamins and enzymes in the intestinal tract, which can help ducks absorb calcium, phosphorus, zinc, copper and iron, meet the needs of duck reproductive performance, and improve male ducks. The quality of semen and the fertilization rate of eggs have avoided various disadvantages caused by the use of antibiotics.
3. Improve the quality of animal products
Clostridium butyricum preparations can regulate the intestinal micro-ecological balance of animals and treat related animal diseases, effectively reduce superinfection and drug residues in animals; increase the content of protein nitrogen in blood, improve protein metabolism, and reduce serum Cholesterol level; the production of various probiotics is beneficial to supplement essential nutrients, maintain normal physiological functions of the body, promote metabolism, improve the quality of livestock, poultry and fishery products, and then ensure that the quality of livestock, poultry and fishery products meets the standards of production, processing, sales and export, To break through the "green barriers" on international traders.
When a certain dose of Clostridium butyricum was added to the feed of broilers, the activity of lipoprotein lipase in the abdominal fat of broilers, the expression of hepatic fatty acid binding protein gene in the jejunal mucosa, the expression of eicosapentaenoic acid and n- The content of 3 unsaturated fatty acids all increased significantly, and the shear force of the muscle was significantly reduced, and for the drip loss in the breast muscle, there was a very significant interaction between the fat in the diet and Clostridium butyricum, which strongly proved that Clostridium butyricum Bacteria can improve the quality of meat products and increase the content of essential unsaturated fatty acids in breast muscles.